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Granulomatosis with polyangiitis in an adolescent male with chronic cough and pulmonary nodules
  1. Wallace Wee1 and
  2. Kevan Dilip Mehta2,3
  1. 1Division of Respiratory Medicine, The Hospital for Sick Children, Toronto, Ontario, Canada
  2. 2Division of Pediatric Respirology, McMaster Children's Hospital, Hamilton, Ontario, Canada
  3. 3Faculty of Health Sciences, McMaster University, Hamilton, Ontario, Canada
  1. Correspondence to Dr Kevan Dilip Mehta; mehtak24{at}


Granulomatosis with polyangiitis (GPA) is a small to medium vessel vasculitis that is uncommon in paediatrics. However, with chronic cough often being the initial symptom, a common complaint and a median age of diagnosis of 14 years, it is nevertheless an important condition for paediatricians to consider as it can otherwise go undiagnosed for a long period of time. In this case report, we discuss a paediatric patient with GPA that presented with non-specific respiratory symptoms for several months and was then found to have pulmonary nodules on chest imaging once a broader differential diagnosis was considered. We will review the common presentation of GPA, the classification criteria and its management. This will ultimately assist any providers in identifying and managing GPA cases.

  • Paediatrics
  • Respiratory medicine
  • Interstitial lung disease
  • Rheumatology
  • Vasculitis

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  • Contributors WW drafted the initial manuscript and reviewed/revised the manuscript. KDM reviewed/revised the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.