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Rare and unexpected cause for isolated massive pericardial effusion in a patient with end-stage renal disease—Brucellosis
  1. Maanasa Bhaskar1,
  2. Soundarya Rajamanikam1,
  3. Sujatha Sistla1 and
  4. Jaya Madhuri Suryadevara2
  1. 1Microbiology, Jawaharlal Institute of Postgraduate Medical Education and Research, Pondicherry, India
  2. 2Medicine, Jawaharlal Institute of Postgraduate Medical Education and Research, Puducherry, Tamil Nadu, India
  1. Correspondence to Dr Sujatha Sistla; sujathasistla{at}


Brucellosis is one of the most common zoonotic infections with worldwide distribution. The clinical presentation of brucellosis ranges from asymptomatic to severe disease involving haematological, gastrointestinal, neurological and osteoarticular systems. Cardiovascular manifestations are rare in brucellosis cases with endocarditis being the most common presentation. Isolated pericarditis with massive pericardial effusion without endocarditis is extremely rare. Here, we describe a case of brucellosis with sole manifestation of pericarditis with massive pericardial effusion in a patient with end stage renal disease diagnosed based on the isolation of Brucella melitensis from pericardial fluid.

  • pericardial disease
  • chronic renal failure
  • infectious diseases

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  • Contributors MB: planning, reporting and preparation of manuscript of the work described. SR: collection of patient data, done laboratory processing of the sample and contributed in manuscript writing. SS: critically reviewed the paper. JMS: provided treatment and care for the study patient, contributed in manuscript writing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.