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Case Reports: Rare disease
Klebsiella invasive syndrome: a challenging diagnosis
  1. Poorva Prashant Bhide,
  2. Apurva Avadhut Ketkar,
  3. Abdalrahman Almeligy and
  4. Anthony Ricca
  1. Internal medicine, Monmouth Medical Center, Long Branch, New Jersey, USA
  1. Correspondence to Dr Poorva Prashant Bhide; poorva.bhide.md{at}gmail.com

Abstract

Klebsiella invasive syndrome is a rare condition that typically presents as a liver abscess with metastatic infection, with mortality rates as high as 14% potentially due to diagnostic delay by clinicians. Here, we present a case of a woman in her 60s, who presented with symptoms and signs consistent with meningitis, imaging findings suggestive of possible leptomeningeal carcinomatosis a long with areas of lung consolidation and abdominal nodules and lymphadenopathy, presumably metastatic malignancy. We diagnosed Klebsiella invasive syndrome and treated it conservatively with medical management, including a long course of intravenous antibiotic therapy and supportive care. This is an infrequently encountered clinical entity with potentially fatal consequences, and we hope to add to the existing literature on the subject and drive home the point that it should be considered in the differential diagnoses in the appropriate clinical scenario.

  • Infectious diseases
  • Urinary tract infections
  • Pneumonia (infectious disease)
  • Meningitis
  • Infections

http://dx.doi.org/10.1136/bcr-2022-251977

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    Footnotes

    • Twitter @poorvabhide

    • Contributors PPB: corresponding (first) author lead-conceptualisation, data collection, visualisation, writing-original draft, writing-review and editing. AAK: supporting-conceptualisation, data collection, visualisation, writing-original draft, review and editing. AA: supporting-conceptualisation, data collection, visualisation, writing-original draft, writing-review and editing. AR: lead-supervision, resources supporting-conceptualisation, data collection, visualisation, writing-original draft, writing-review and editing.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.