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Case Reports: Unusual association of diseases/symptoms
Synchronous carcinoma of thyroglossal duct cyst and native thyroid gland
  1. K Devaraja1,
  2. Sumeet Suresh Malapure2,
  3. R Neeraj1 and
  4. Deepa Hunasaghatta Chandrappa3
  1. 1Otorhinolaryngology and Head and Neck Surgery, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
  2. 2Division of Nuclear Medicine, Radiotherapy, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
  3. 3Pathology, Kasturba Medical College, Manipal, Manipal Academy of Higher Education, Manipal, Karnataka, India
  1. Correspondence to Dr K Devaraja; deardrdr{at}gmail.com

Abstract

The unobliterated portion of embryological thyroglossal duct may present as cystic swelling later in life and may contain functional thyroid follicles. This cyst requires excision along with the entire thyroglossal duct remnant and adjacent portion of hyoid bone. At times, the excised specimen could demonstrate a focus of carcinomatous change inside the cyst wall. Very rarely, this thyroglossal duct cyst carcinoma could be associated with malignancy of native thyroid gland. This case report illustrates an interesting case of synchronous carcinoma of thyroglossal duct cyst and native thyroid gland. It also sheds light on the controversies related to the pathophysiology of such association and the dilemmas surrounding the management of thyroglossal duct cyst carcinoma, with or without concurrent carcinoma of thyroid gland.

  • Ear, nose and throat/otolaryngology
  • Thyroid disease
  • Endocrine cancer
  • Head and neck surgery
  • General surgery

http://dx.doi.org/10.1136/bcr-2022-250853

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    Footnotes

    • Contributors KD was involved in all stages of patient care and in manuscript writing, analysis and submission. SSM was involved in all stages of patient care and in manuscript analysis and submission. RN was involved in patient care, manuscript writing and submission. DHC was involved in patient care and in manuscript analysis and submission.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.