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Case of myocarditis secondary to severe Plasmodium falciparum infection
  1. Angharad Langdon,
  2. Ihab Abdlaziz,
  3. Kim Rhodes and
  4. Jayson Clarke
  1. Department of Anaesthetics and Intensive Care Medicine, Lewisham and Greenwich NHS Trust, London, UK
  1. Correspondence to Dr Angharad Langdon; angharad.langdon{at}


Malaria remains one of the most prevalent infectious diseases globally. Despite targets set out by the WHO in 2015, there has been a rise in the number of cases since 2019 as an indirect effect of the COVID-19 pandemic.

Cardiac complications are very rarely witnessed with severe malaria. Of the cardiac sequelae, myocarditis is one of the most frequently observed with a handful of case reports in the literature. We report a case of a man in his 50s who developed myocarditis while being managed for severe Plasmodium falciparum malaria in an intensive care unit in the UK and review the literature relevant to this case. This is the second reported case of this condition in the UK.

  • Adult intensive care
  • Tropical medicine (infectious disease)
  • Global Health
  • Heart failure

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  • Contributors AL, IA, KR and JC were directly involved in the patient care. AL and KR wrote the manuscript in consultation with IA and JC.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.