Article Text

Download PDFPDF
MRI-negative myelitis associated with cerebral venous thrombosis after COVID-19 infection
  1. Dea Masaad1,
  2. Shaza Youssef2,
  3. Mhd Firas Safadi3 and
  4. Mohamad Shehadeh Agha1
  1. 1Department of Neurology, Al-Mouwasat Hospital, Damascus, Syrian Arab Republic
  2. 2Primary Health Care Corporation, Doha, Qatar
  3. 3Department of Visceral, Thoracic and Vascular Surgery, University Hospital Carl Gustav Carus, Dresden, Sachsen, Germany
  1. Correspondence to Dr Mhd Firas Safadi; doctor.safadi{at}


Transverse myelitis and cerebral venous thrombosis represent some of the described neurological complications of coronavirus disease. A woman in her early 30s presented with headache, left-sided sensory symptoms and voiding difficulty. The patient also reported dry cough, fever, nasal congestion, anosmia and ageusia 2 weeks before presentation. The clinical examination showed sensory disturbances on the left side of the body, starting from the lower abdomen and extending to the left leg, which was consistent with transverse myelitis. The laboratory assessment confirmed a previous infection with coronavirus disease and excluded autoimmune entities. Radiological investigations revealed left transverse sinus thrombosis with no spinal cord abnormalities. The treatment was started with therapeutic anticoagulation and intravenous high-dose steroids. The patient showed significant improvement, and the neurological deficits resolved after 3 months. This is the first documented case of imaging-negative myelitis associated with cerebral venous thrombosis after coronavirus disease.

  • Spinal cord
  • Headache (including migraines)
  • Neurology
  • Respiratory medicine

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors DM treated and followed the patient, gathered the data, researched the literature and wrote the first draft. SY selected the figures, wrote the figure captions and discussed the radiological aspects of the case. MFS organised the literature review and edited the discussion. MSA reviewed the article for scientific adequacy and improved the discussion. All authors reviewed and approved the final manuscript before submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.