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Effect of pregnancy and lactation on a benign phyllodes tumour
  1. Li Yin Ooi1,
  2. Geok Hoon Lim2 and
  3. Mihir Ananta Gudi3
  1. 1Department of Pathology, National University Hospital, Singapore
  2. 2Breast Department, KK Women's and Children's Hospital, Singapore
  3. 3Department of Pathology, KK Women's and Children's Hospital, Singapore
  1. Correspondence to Dr Mihir Ananta Gudi; Gudi.Mihir.A{at}


Phyllodes tumours occurring in pregnancy are very rare. While most cases presented as rapidly enlarging masses, we present a benign phyllodes tumour which had the most growth in the first half of pregnancy followed by gradual growth in the latter half of pregnancy and lactation, as characterised on ultrasound imaging. This is the first report, to the best of our knowledge, which has objective measurements of the lesion before, during and after pregnancy. It also highlighted the need for a vigilant approach to fibroepithelial lesions in pregnancy, instead of attributing the growth of these lesions solely to hormonal changes.

  • breast surgery
  • pathology
  • ultrasonography

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  • Contributors GHL and MAG conceptualised the case report and acquired the data for the article. GHL obtained the patient consent. LYO prepared the manuscript with important intellectual input from GHL and MAG. LYO, GHL and MAG approved the final version of the manuscript. GHL and MAG are responsible for the overall content as guarantors.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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