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Drug use-related right-sided infective endocarditis complicated by empyema and bronchopleural fistula
  1. Lindsey M Shain1,
  2. Taha Ahmed2,
  3. Michele L Bodine3 and
  4. Jennifer G Bauman3
  1. 1University of Kentucky College of Medicine, Lexington, Kentucky, USA
  2. 2Divison of Hospital/Internal Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA
  3. 3Advanced Practice Provider Residency Program, Division of Hospital Medicine, University of Kentucky College of Medicine, Lexington, Kentucky, USA
  1. Correspondence to Dr Taha Ahmed; tahaahmedfairview{at}


Right-sided infective endocarditis is frequently accompanied by septic pulmonary emboli, which may result in a spectrum of respiratory complications. We present the case of a 25-year-old woman diagnosed with infective endocarditis secondary to intravenous drug use. During a long and arduous hospital course, the patient developed empyema with bronchopleural fistula, representing severe but uncommon sequelae that may arise from this disease process. She was treated with several weeks of antibiotics as well as surgical thorascopic decortication and parietal pleurectomy.

  • valvar diseases
  • infectious diseases
  • mechanical ventilation
  • pleural infection

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  • Contributors LMS performed the literature review, drafted the manuscript and reviewed the manuscript. TA designed the study and reviewed the manuscript. MLB and JGB reviewed the manuscript and suggested pertinent modifications.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.