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Rare yet catastrophic presentation of undiagnosed antiphospholipid syndrome
  1. Seojung Kwak and
  2. Malcolm Green
  1. General Medicine, Tamworth Rural Referral Hospital, Tamworth, New South Wales, Australia
  1. Correspondence to Dr Seojung Kwak; seojung.kwak{at}


A previously well 31-year-old woman initially presented to the emergency department with pneumonia, however, was found to be hypertensive and have new-onset cardiomegaly. She was admitted for intravenous antibiotics and concurrently a series of investigations were conducted to investigate hypertension and cardiomegaly. During the course of admission, she developed acute kidney injury and was found to have acute chronic occlusion in the abdominal aorta. She was diagnosed with catastrophic antiphospholipid syndrome. This is a rare form of antiphospholipid syndrome with a high mortality rate. Thus, it is important that clinicians are aware of this syndrome to facilitate early diagnosis and initiation of treatment.

  • renal medicine
  • rheumatology

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  • Contributors All authors contributed substantially to the authorship and review and editing of the final document. SK was responsible for the initial write-up. MG assisted with writing and supervised the overall project.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Case reports provide a valuable learning resource for the scientific community and can indicate areas of interest for future research. They should not be used in isolation to guide treatment choices or public health policy.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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