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Spontaneous intracardiac contrast in a case with intestinal pneumatosis
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  1. Martin Leth-Olsen1,2,
  2. Øystein Drivenes3,
  3. Wendy Williams1 and
  4. Siri Ann Nyrnes1,2
  1. 1Children's Clinic, St Olavs Hospital University Hospital in Trondheim, Trondheim, Norway
  2. 2Department of Circulation and Medical Imaging, Faculty of Medicine and Health Sciences, NTNU—Norwegian University of Science and Technology, Trondheim, Norway
  3. 3Department of Paediatric Surgery, St Olavs Hospital University Hospital in Trondheim, Trondheim, Norway
  1. Correspondence to Dr Martin Leth-Olsen; martin.leth-olsen{at}ntnu.no

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Description

A 4-year-old girl, treated with immunosuppressive medication due to relapse of haemophagocytic lymphohistiocytosis, developed gastroenteritis with norovirus. She showed clinical improvement initially, but her symptoms and shedding of norovirus RNA persisted for many weeks. On day 19, she had increasing reports of stomach cramps, an episode of vomiting and episodes of blood in her stool. On examination, she had persisting tachycardia (heart rate 140 bpm), her blood pressure fell (80/45 mm Hg), but central capillary refill time remained normal. Her stomach was painful on deep palpation, but soft and with normal bowel sounds. Laboratory findings revealed a slight increase in c-reactive protein (11 mg/L), a drop in sodium (128 mmol/L) and persistent pancytopenia (haemoglobin 93 g/L, white cell count 0.9×109 /L, neutrophil granulocytes 0.73×109 /L, thrombocytes 19×109 /L).

Due to the drop in blood pressure and in order to guide fluid managements, an echocardiogram was performed (video 1).

Video 1

The echocardiogram revealed massive amounts of air bubbles in the right atrium and right ventricle, and, furthermore, a noticeable amount of air bubbles in the left heart. Gaseous embolisation from the intestines was suspected. The following abdominal X-ray revealed pneumatosis and possible intrahepatic air. The patient’s symptoms progressed rapidly with respiratory and circulatory deterioration. She was therefore rushed to the operating theatre where laparotomy confirmed pneumatosis in the entire colon and distal ileum (figure 1). Surgical colectomy and ileostomy to remove the source of air embolisation were performed. Histology showed pseudomembranous colitis-like changes with large amounts of air in the mucosa and submucosa. A second look laparotomy 1 day after the colectomy showed viable and well-perfused remaining intestines. A period of challenging intensive care was followed. She had large amounts of hypersecretion from remaining intestine and fluid loss consistent with short bowel syndrome. Three months after the embolisation, a successful allogenic stem cell transplantation was performed. The patient survived and is doing well today.

Figure 1

Pneumatosis of the colon.

Gaseous embolisation from the intestines is rare.1 This case demonstrates that echocardiography is an ideal imaging modality for rapid assessment of the circulation in critically ill patients.2 3 In this case, echocardiography guided the clinician to the right diagnosis.

Learning points

  • Echocardiography is an essential diagnostic tool in the critically ill patient’s assessment.

  • Gaseous embolisation from intestines is rare but severe and requires immediate attention.

  • Immunocompromised patients with norovirus-gastroenteritis can experience a prolonged and more severe illness.

Ethics statements

Patient consent for publication

Acknowledgments

We are most thankful for the contributions from all involved clinicians at The Childrens clinic at St Olavs hospital.

References

Footnotes

  • Contributors All authors have each made a substantial contribution and qualify for authorship. The final version of the manuscript has been evaluated by all authors. ØD, WW and SAN were involved in patient care. Conception and design: SAN and ML-O. Acquisition of data: the data material includes the patients’ medical journal as well as medical images. SAN and ML-O provided access to the data material. ML-O has communicated with the patient’s parents to get consent. Analysis and interpretation of data material: SAN and ML-O. Drafting the manuscript: ML-O. Revising the manuscript: SAN, ØD, WW and ML-O have all been involved in revising the manuscripts for important intellectual content. All authors have contributed to the manuscript in a substantial way. Final approval of the version published: SAN, ØD, WW and ML-O have all approved the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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