Article Text

Download PDFPDF
Xanthogranulomatous pyelonephritis due to Aspergillus in a non-diabetic older patient
  1. Neha Khilar1,
  2. Navneet Gupta1,
  3. Prabha Adhikari2 and
  4. Abhijith Rajaram Rao2
  1. 1Internal Medicine, Yenepoya Medical College Hospital, Mangalore, Karnataka, India
  2. 2Geriatric Medicine, Yenepoya Medical College Hospital, Mangalore, Karnataka, India
  1. Correspondence to Dr Abhijith Rajaram Rao; abhijith.rrao{at}


Xanthogranulomatous pyelonephritis is a rare condition characterised by destructive granulomatous inflammation of renal parenchyma. Primary renal Aspergillosis has been reported in patients with immunocompromised states such as diabetes, retroviral disease, organ transplant recipients, etc. We present a unique case of an older adult in his early 60s, presenting with fever and left flank pain with renal angle tenderness, diagnosed with primary renal aspergillosis with xanthogranulomatous pyelonephritis. These symptoms resolved with a long duration of antifungal (itraconazole) therapy and nephrectomy. The unique features are the development of fungal pyelonephritis in the absence of any immunocompromising conditions and the development of xanthogranulomatous changes with no risk factors.

  • infections
  • urinary tract infections

Statistics from

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.


  • Contributors NK: Drafting the work; NG: acquisition and analysis of data; PA: conception of the work, revising; ARR: Drafting, reviewing the final draft, and formatting of the work as per the journal’s requirement; All authors were involved in patient care.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.