Haemophagocytic lymphohistiocytosis (HLH) causing multiorgan failure has been reported as an acute clinical presentation of COVID-19. However, the literature surrounding HLH in the context of a postacute COVID-19 syndrome is limited. This report presents a case of a life-threatening HLH occurring 6 weeks after a pauci-symptomatic COVID-19 infection in a previously healthy adult. A bone marrow aspirate confirmed the HLH and the patient was successfully treated with dexamethasone and etoposide. To our knowledge, this is the first case of HLH occurring as a postacute COVID-19 syndrome following a pauci-symptomatic initial infection.
- adult intensive care
- haematology (incl blood transfusion)
- malignant and benign haematology
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Contributors DW and GS devised the project and main conceptual ideas. DW reviewed the patient’s chart and wrote the manuscript under the supervision of J-PR and GS. J-PR provided the photos of the bone marrow aspirate. DW created the tables. GS, J-PR and JL provided feedback and helped shape the analysis and the manuscript.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.