Article Text

Download PDFPDF
Persistent COVID-19 lung infection in a child with a primary immunodeficiency
  1. Sarah Fernández-Suárez1,2,
  2. Giuliana Reyes-Florian1,3,
  3. Pablo Vásquez-Hoyos4,5 and
  4. Jesús Angel Domínguez-Rojas1,6
  1. 1Departamento de Pediatría, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru
  2. 2Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Peru
  3. 3Facultad de Medicina, Universidad Ricardo Palma Facultad de Medicina Humana, Lima, Peru
  4. 4Pediatria, Universidad Nacional de Colombia, Bogota, Bogota, Colombia
  5. 5Pediatria, Fundacion Universitaria de Ciencias de la Salud, Bogotá, Colombia
  6. 6Pediatric critical care department, Instituto Nacional de Salud del Niño, Lima, Peru
  1. Correspondence to Dr Jesús Angel Domínguez-Rojas; jesusdominguez24{at}gmail.com

Abstract

SARS-CoV-2 infection in children with primary immunodeficiency disease (PID) and its complications have not yet been well described, the course of COVID-19 can range from mild illness to death. We aim to report the case of a child with a PID who develop a severe and persistent pulmonary COVID-19 infection. We present chronologically his clinical course, tests, interventions and radiological findings showing his irregular evolution and poor response to infection. This case highlights the need to accurately monitor the immune response in these cases to try to stop the progression of the damage.

  • COVID-19
  • pneumonia (infectious disease)
  • paediatric intensive care
  • immunology

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

Statistics from Altmetric.com

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.

Footnotes

  • Twitter @pvasquezcolpicu

  • Contributors SF-S and GR-F drafted the manuscript and collected the data. JAD-R edited the manuscript. PV-H reviewed and edited the manuscript. All authors reviewed and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.