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Persistent COVID-19 lung infection in a child with a primary immunodeficiency
  1. Sarah Fernández-Suárez1,2,
  2. Giuliana Reyes-Florian1,3,
  3. Pablo Vásquez-Hoyos4,5 and
  4. Jesús Angel Domínguez-Rojas1,6
  1. 1Departamento de Pediatría, Hospital Nacional Edgardo Rebagliati Martins, Lima, Peru
  2. 2Facultad de Medicina, Universidad Nacional Federico Villarreal, Lima, Peru
  3. 3Facultad de Medicina, Universidad Ricardo Palma Facultad de Medicina Humana, Lima, Peru
  4. 4Pediatria, Universidad Nacional de Colombia, Bogota, Bogota, Colombia
  5. 5Pediatria, Fundacion Universitaria de Ciencias de la Salud, Bogotá, Colombia
  6. 6Pediatric critical care department, Instituto Nacional de Salud del Niño, Lima, Peru
  1. Correspondence to Dr Jesús Angel Domínguez-Rojas; jesusdominguez24{at}


SARS-CoV-2 infection in children with primary immunodeficiency disease (PID) and its complications have not yet been well described, the course of COVID-19 can range from mild illness to death. We aim to report the case of a child with a PID who develop a severe and persistent pulmonary COVID-19 infection. We present chronologically his clinical course, tests, interventions and radiological findings showing his irregular evolution and poor response to infection. This case highlights the need to accurately monitor the immune response in these cases to try to stop the progression of the damage.

  • COVID-19
  • pneumonia (infectious disease)
  • paediatric intensive care
  • immunology

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  • Contributors SF-S and GR-F drafted the manuscript and collected the data. JAD-R edited the manuscript. PV-H reviewed and edited the manuscript. All authors reviewed and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.