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Rare presentation of choroidal neovascularisation in a case of congenital hypertrophy of retinal pigment epithelium
  1. Ramesh Venkatesh1,
  2. Nikitha Gurram Reddy1,
  3. Ram Snehith Pulipaka1 and
  4. Arpitha Pereira2
  1. 1 Department of Retina and Vitreous, Narayana Nethralaya, Bangalore, India
  2. 2 Department of Ophthalmology, Abergele Hospital, Abergele, UK
  1. Correspondence to Dr Arpitha Pereira; arpitha.pereira{at}


A 22-year-old woman presented with a 2-week history of decreased vision, a central scotoma and metamorphopsia in her right eye. Her presenting visual acuity was 6/75 in the right eye and 6/6 in the left eye. Anterior segment examination was normal. Fundus examination of both eyes showed features of bilateral congenital hypertrophy of retinal pigment epithelium (CHRPE) lesions and choroidal neovascularisation (CNV) in the right eye. She was treated with intravitreal injection bevacizumab 1.25 mg/0.05 mL. One month later, there was regression of the CNV and subretinal fluid and her vision improved to 6/12. At the final follow-up visit, her vision was maintained at 6/9 with regression of CNV noted. To conclude, CNV is a rare association of CHRPE. It can lead to vision-threatening problem if it involves the macula and should be identified promptly and managed appropriately.

  • macula
  • retina

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  • Contributors RV and AP: case management and manuscript writing. NGR and RSP: data collection and initial draft of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.