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Rare case of diffuse large B-cell lymphoma presenting with central pontine myelinolysis
  1. Phillip Cuong Nguyen1,
  2. Megan Dunstan2,
  3. Beena Kumar3 and
  4. Michael Sze Yuan Low1,4
  1. 1Monash Haematology, Monash Medical Centre Clayton, Melbourne, Victoria, Australia
  2. 2Neurology, Monash Health, Clayton, Victoria, Australia
  3. 3Department of Anatomical Pathology, Monash Health, Clayton, Victoria, Australia
  4. 4Faculty of Medicine Nursing and Health Sciences, Monash University, Clayton, Victoria, Australia
  1. Correspondence to Dr Michael Sze Yuan Low; michael.low{at}


Central pontine myelinolysis (CPM) is commonly associated with osmotic stress and rapid correction of hyponatraemia. It has rarely been reported in conjunction with malignancies. We report a case where CPM was not only associated with a new diagnosis of diffuse large B-cell lymphoma but was also a key presenting feature.

  • haematology (incl blood transfusion)
  • neuroimaging

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  • Contributors PCN, MD and MSYL directed care for the patient. BK provided expert pathology support and provided the diagnosis. All authors have reviewed and approved the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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