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IgG4-related hepatic inflammatory pseudotumour: could MRI suggest the correct diagnosis?
  1. Ana Primitivo1,
  2. Maria Helena Oliveira2 and
  3. Afonso Gonçalves1,3
  1. 1Radiology, Hospital Beatriz Ângelo, Loures, Portugal
  2. 2Pathology Department, Hospital Beatriz Ângelo, Loures, Portugal
  3. 3Radiology, Hospital Garcia de Orta EPE, Almada, Portugal
  1. Correspondence to Dr Ana Primitivo; anaprimitivo{at}gmail.com

Abstract

We report a case of a 62-year-old woman, HIV positive, with a 3-week history of jaundice and elevated cholestatic enzymes. Imaging studies displayed intrahepatic biliary dilatation and a central liver lesion. Pathology described lesions of active cholangitis, lymphoplasmacytic infiltration and fibrosis, suggesting a hepatic inflammatory pseudotumour (IPT) IgG4 related. IgG4-related lymphoplasmacytic form of IPT belongs to IgG4-related diseases. We discuss the importance to include IgG4-related hepatic IPT as part of the differential diagnosis of any liver lesion, highlighting potential imaging clues that may help in establishing the correct diagnosis.

  • radiology (diagnostics)
  • gastrointestinal system
  • liver disease

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Footnotes

  • Contributors AP reviewed the literature and wrote the first draft. AG discussed the case in the multidisciplinary meeting and also reviewed the literature. MHO provided the histological diagnosis and the image used in this section. All authors reviewed and edited the manuscript and approved the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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