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Unusual cause of resistant hypertension in a 33-year-old woman with a palpable parathyroid nodule


A 33-year-old woman presented for investigation for a secondary cause of her long-standing treatment-resistant hypertension. Physical examination revealed a palpable thyroid nodule with subsequent ultrasound and CT scan indicating the nodule was of parathyroid origin. A palpable parathyroid nodule is known to be highly suspicious for a parathyroid carcinoma, and it remains a differential until proven otherwise. Histopathology following surgical excision confirmed a parathyroid adenoma, and during subsequent follow-up visits with her general practitioner, her antihypertensive was successfully weaned. We report a case of a large palpable parathyroid adenoma being the secondary cause of treatment-resistant hypertension.

  • general practice / family medicine
  • oncology
  • hypertension
  • cardiovascular medicine

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