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Large mural thrombus in the distal arch of the aorta without atherosclerotic disease
  1. Mohammed M Uddin1,
  2. Mohamad Amer Soudan1,
  3. Joseph Sebastian2,
  4. Tanveer Mir2,
  5. Said Ashraf3 and
  6. Luis Afonso4
  1. 1Internal Medicine, Wayne State University, Warren, Michigan, USA
  2. 2Internal Medicine, Detroit Medical Center, Detroit, Michigan, USA
  3. 3Department of Interventional Cardiology, NYC Health and Hospitals-Bellevue, New York, NY, USA
  4. 4Department of Cardiovascular Disease, Detroit Medical Center, Wayne State University, Detroit, MI, USA
  1. Correspondence to Dr Mohammed M Uddin; mohammed.uddin2{at}


Aortic mural thrombus (AMT) is an uncommon cause of arterial thromboembolism. It is very rare in patients without significant cardiovascular risk factors. Many aetiologies can cause AMT, but there are no clear guidelines for the evaluation and treatment. We present the case of a 43-year-old woman without arteriosclerotic disease who was admitted to the hospital with peripheral embolisation from the mural thrombus in the distal arch of the aorta. Therapy with systemic anticoagulation resulted in complete resolution without necessitating any surgical or endovascular interventions. There were no reported recurrence or complications of the intra-aortic thrombus within 1-year surveillance imaging study.

  • cardiovascular medicine
  • venous thromboembolism
  • radiology (diagnostics)

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  • MMU and MAS are joint first authors.

  • Contributors MMU, MAS, JS have helped with the conception, design and abstract for this paper. MMU, MAS, JS, TM and SA have helped with writing case presentation, discussion section, data collection from the EMR including lab findings and medical histories, echocardiography image collection from cardiology echocardiography lab, collecting CT scan images in addition to talking to radiologist for deeper interpretation of the images in the study. MMU, MAS, JS, TM, and SA have collected all the citations, interpreting the summary of each citation article, and worked on in-text citations that are relevant to the article. LA was the senior author of this article who gave final recommedations for submission.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.