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Atypical case of mild encephalopathy/encephalitis with reversible splenial lesion of the corpus callosum (MERS) associated with Mycoplasma pneumoniae infection in a paediatric patient
  1. Asra Akbar1 and
  2. Sharjeel Ahmad2
  1. 1Pediatric Neurology, UICOMP, Peoria, Illinois, USA
  2. 2Internal Medicine, Section of Infectious Diseases, University of Illinois College of Medicine at Peoria, Peoria, Illinois, USA
  1. Correspondence to Dr Asra Akbar; aakbar1{at}


Mild encephalopathy with reversible splenial lesion (MERS) is a disorder characterised by prodromal symptoms such as fever, cough, vomiting or diarrhoea, followed by mild encephalopathy 1–7 days later with a documented reversible corpus callosum splenial lesion. MERS is mostly reported in children in the region of East Asia. To the best of our knowledge, this is the first reported case of MERS associated with mycoplasma infection in a child in North America. A brief review of literature is also a part of this report.

  • infection (neurology)
  • epilepsy and seizures
  • cranial nerves

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  • Contributors AA wrote the initial manuscript. SA and AA conceptualised the draft and was responsible for data design and image collection. SA and AA reviewed the final manuscript. All authors agreed with the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.