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Case report
COVID-19: a confirmed case of reinfection in a nurse
  1. Giuliana Scarpati,
  2. Ornella Piazza,
  3. Pasquale Pagliano and
  4. Francesca Rizzo
  1. Università degli Studi di Salerno, Dipartimento di Medicina, Chirurgia, Odontoiatria "Scuola Medica Salernitana", Baronissi, Baronissi (SA), Italy
  1. Correspondence to Professor Ornella Piazza; opiazza{at}unisa.it

Abstract

We describe the case of a 63-year-old man who is reported to have the first confirmed case of COVID-19 reinfection in Campania Region, Italy. We found that the two episodes were caused by virus strains with clearly different genome sequences. The patient, a retired nurse, had a very low level of antibodies IgG directed against the spike protein 14 days after his first Pfizer/BioNTek vaccine shot.

  • COVID-19
  • immunological products and vaccines
  • pneumonia (infectious disease)
  • adult intensive care

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2021-244507

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    Footnotes

    • Contributors Conception and design, acquisition of data (clinical data GS: genomics FR). Analysis and interpretation of data (OP and PP). Drafting the article or revising it critically for important intellectual content (OP, GS, FR and PP). Final approval of the version published (OP, GS, FR and PP). Agreement to be accountable for the article and to ensure that all questions regarding the accuracy or integrity of the article are investigated and resolved. (OP, GS, FR and PP).

    • Funding Regione Campania grant GENOMAeSALUTE, POR Campania FESR 2014/2020, azione 1.5; CUP: B41C17000080007; grant 'Monitoring the spread and genomic variability of the Covid 19 virus in Campania using NGS technology' (N/A).

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.