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Rare case of gastrointestinal mucormycosis with colonic perforation in an immunocompetent patient with COVID-19
  1. Ravinder Pal Singh1,
  2. Nishkarsh Gupta2,
  3. Tanudeep Kaur3 and
  4. Anju Gupta4
  1. 1Department of Liver Transplant, Hepatobiliary and gastro intestinal surgery, Saroj Super Speciality Hospital, New Delhi, Delhi, India
  2. 2Department of Onco-Anesthesiology and Palliative Medicine, DRBRAIRCH, AIIMS, New Delhi, Delhi, India
  3. 3Department of Urogynaeoncology, Saroj Hospital and Heart Institute, New Delhi, Delhi, India
  4. 4Department of Anesthesiology, Pain Medicine and Critical care, AIIMS, New Delhi, Delhi, India
  1. Correspondence to Anju Gupta; dranjugupta2009{at}
  • Present affiliation The present affiliation of Anju Gupta is: R.No. 6, 4th floor, Porta Cabin, Teaching Block, AIIMS, Ansari Nagar, New Delhi 110029, India


Primary gastrointestinal mucormycosis is a rare disease associated with an increased mortality and is rarely reported in an immunocompetent host. We report the first case of mucormycosis-associated colonic perforation in a COVID-19 patient with a favourable outcome. A 48-year-old healthy male doctor in home isolation due to COVID-19 was admitted to COVID-19 intensive care unit when his symptoms deteriorated. The patient was put on non-invasive ventilation (NIV) using Bilevel Positive Airway Pressure (BiPAP) and treatment given as per existing hospital protocol. The patient improved clinically, and was discharged on day 10 of admission. Two days later, he presented with acute gastrointestinal symptoms to the emergency department. A diagnosis of perforation peritonitis was made, the patient was stabilised and sigmoid colectomy with descending colon colostomy was done. A diagnosis of gastrointestinal mucormycosis was made and injectable antifungal was started. The patient was discharged after his general conditions improved.

  • COVID-19
  • infections
  • infection (gastroenterology)
  • adult intensive care
  • general surgery

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  • RPS and NG contributed equally.

  • Contributors RPS did the case, helped in collecting and analysis of data, literature search, writing the manuscript critical review. NG helped in concept and design, collecting, analysis and interpretation of data, literature search, writing the manuscript and critical review. TK helped in supervision, writing the manuscript and critical review. AG helped in concept and design, collecting, analysis and interpretation of data, literature search, writing the manuscript and critical review. RS helped in writing and critical review of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.