Article Text

Download PDFPDF
Optic nerve perineuritis and retroperitoneal panniculitis: rare first presentations of Behçet’s disease
  1. Katsunobu Yoshioka1 and
  2. Eiko Morita2
  1. 1Internal Medicine, Shitennoji Hospital, Osaka, Japan
  2. 2Ophthalmology, Shitennoji Hospital, Osaka, Japan
  1. Correspondence to Dr Katsunobu Yoshioka; kyoshioka{at}shitennoji-fukushi.jp

Abstract

A 46-year-old woman was admitted to our hospital because of high fever and lumbago. CT revealed increase in density of fat tissue around the aorta, suggesting retroperitoneal panniculitis. The following day, she reported of leg pain, pain in the mouth, painful urination and right eye pain that was exacerbated by eye movement. We observed erythema nodosum, aphthous stomatitis and genital ulceration. Ophthalmologic examination revealed mild right optic disc oedema. Visual acuity was normal in both eyes. MRI with gadolinium infusion revealed enhancement around the right optic nerve, suggesting optic nerve perineuritis (ONP). A diagnosis of Behçet’s disease was made. She was treated with prednisolone and colchicine with a favourable response. A warning sign of ONP is eye pain that is exacerbated by eye movement. MRI with gadolinium infusion should be performed immediately in such cases to prevent vision-threatening sequelae.

  • eye
  • rheumatology

Statistics from Altmetric.com

Footnotes

  • Contributors KY: reviewed medical records, interpreted data and drafted the manuscript. EM: reviewed medical records, interpreted data and supervised the study.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

Request Permissions

If you wish to reuse any or all of this article please use the link below which will take you to the Copyright Clearance Center’s RightsLink service. You will be able to get a quick price and instant permission to reuse the content in many different ways.