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Malakoplakia prostate presenting as urinary retention: a report of two cases and review of the literature
  1. Swaroop Subbaraya,
  2. Ajit Sawant,
  3. Prakash Pawar and
  4. Sunil Patil
  1. Department of Urology, LTMMC & GH, Mumbai, Maharashtra, India
  1. Correspondence to Dr Swaroop Subbaraya; swaroop0appu{at}


Malakoplakia is a rare chronic inflammatory condition, which primarily occurs in genitourinary tract, with prostatic malakoplakia being extremely rare. We present two cases of acute urinary retention, with clinically firm nodular prostate and a raised serum prostate-specific antigen. Transrectal ultrasound-guided prostatic biopsy showed features of malakoplakia. There was a significant reduction of size of prostate on transrectal ultrasonography after 4 weeks of antibiotics. However, one patient had failed trial without catheter and was subjected to transurethral resection of prostate. The biopsy of the prostatic chips also showed features of malakoplakia. Other patient improved symptomatically after antibiotics and was managed conservatively. Both the patients are on regular follow-up and are asymptomatic. Prostatic malakoplakia presenting as urinary retention is very uncommon with around 12 cases in the literature. Recognition of prostatic malakoplakia is important because clinically it can masquerade prostatic malignancy. Treatment with antibiotics is necessary before subjecting the patients for surgery in patients with obstructive symptoms.

  • prostate
  • urinary tract infections
  • urological surgery

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  • Contributors SS: Did extensive research of literature, planning and management of the cases and follow up of the cases. AS and PP: Planning and management of the case. SP: Planning and management of the case and inputs in writing manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.