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Apoplexy in a previously undiagnosed pituitary macroadenoma in the setting of recent COVID-19 infection
  1. Su-Yi Liew1,
  2. Rachel Seese1,
  3. Abdulrahman Shames1 and
  4. Kalpita Majumdar2
  1. 1Barts Health NHS Trust, London, UK
  2. 2Diabetes and Endocrinology, Barts Health NHS Trust, London, UK
  1. Correspondence to Dr Abdulrahman Shames; abdul_shames{at}


Pituitary apoplexy is an endocrine emergency, which commonly presents as hypopituitarism. Prompt diagnosis and treatment can be both life and vision saving. There are a growing number of published case reports postulating a link between COVID-19 and pituitary apoplexy. We report the case of a 75-year-old man who presented with a headache and was later diagnosed with hypopituitarism secondary to pituitary apoplexy. This occurred 1 month following a mild-to-moderate COVID-19 infection with no other risk factors commonly associated with pituitary apoplexy. This case, therefore, supplements an emerging evidence base supporting a link between COVID-19 and pituitary apoplexy.

  • COVID-19
  • endocrinology
  • pituitary disorders

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  • Contributors KM oversaw the writing and editing of the case report, obtained the images used in the case report. S-YL was responsible for researching, planning and writing the introduction and abstract. RS was responsible for researching, planning and writing the discussion and learning points. AS was responsible for researching and writing the case summary and abstract, liaising with the patient and compiling together the sections of the report and submitting it. All authors gave final approval for submission of the case report. All authors agreed to be accountable for all aspects of the submitted case report.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.