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Insulin can be used to treat severe hypertriglyceridaemia in pregnant women without diabetes
  1. Aleena Shujaat Ali1,2,3
  1. 1Endocrinology, Barwon Health, Geelong, Victoria, Australia
  2. 2Obstetric Medicine, Mercy Hospital for Women, Heidelberg, Victoria, Australia
  3. 3Endocinology, Austin Health, Melbourne, Victoria, Australia
  1. Correspondence to Dr Aleena Shujaat Ali; aleena.ali{at}


Severe hypertriglyceridaemia can lead to acute pancreatitis, which is associated with maternal and perinatal mortality when it occurs in pregnancy. Rapid reduction of triglyceride levels is a primary goal in the management of severe hypertriglyceridaemia, however, there are limited safe option for treatment in pregnancy. We present a case of a woman without diabetes presenting with severe hypertriglyceridaemia in late gestation who was safely and successfully treated with insulin and review the literature surrounding the management of this important condition.

  • lipid disorders
  • endocrinology
  • metabolic disorders
  • pancreatitis
  • pregnancy

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  • Contributors ASA treated the case patient and is responsible for the case report, literature review and figures in this article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.