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Case report
Severe acquired haemophilia associated with asymptomatic SARS-CoV-2 infection
  1. Kevin Y Wang1,
  2. Pratik Shah1,
  3. Dennis T Roarke2 and
  4. Shams A Shakil3
  1. 1Department of Internal Medicine, NSLIJ Health System, New Hyde Park, New York, USA
  2. 2Department of Internal Medicine, Northwell Health, New Hyde Park, New York, USA
  3. 3Department of Hematology Oncology, Northwell Health, New Hyde Park, New York, USA
  1. Correspondence to Dr Kevin Y Wang; Kevwangyu{at}gmail.com

Abstract

A 65-year-old man presented with symptoms of severe subcutaneous bleeding in his arm, which led to compartment syndrome requiring fasciotomy and massive blood transfusion protocol. Medical history was significant for history of autoimmune thyroid disease. Workup revealed elevated partial thromboplastin time, decreased factor VIII levels and elevated factor VIII inhibitor levels. He was worked up for causes of acquired haemophilia A and was found to have an elevated SARS-CoV-2 antibody level. Given his negative workup for other secondary aetiologies, we suspect that the cause of his haemophilia A was from his SARS-CoV-2 infection, which has been observed previously in various case reports.

  • COVID-19
  • Haematology (drugs and medicines)

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https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2021-242884

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    Footnotes

    • Contributors KW wrote the initial draft and edited draft. PS assisted in editing the draft and contributing ideas. DTR assisted in editing the draft and contributing ideas. SAS assisted in editing the draft and contributing ideas.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer-reviewed.