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Elderly woman presenting with multivessel coronary artery disease and Takotsubo syndrome
  1. Hari Vivekanantham1,
  2. Martin Scoglio2,
  3. Philipp Suter2,
  4. Stephane Cook1,
  5. Yann Roux1 and
  6. Diego Arroyo1
  1. 1Department of Cardiology, HFR Fribourg Hôpital cantonal, Fribourg, Switzerland
  2. 2Department of Internal Medicine, HFR Fribourg Hôpital cantonal, Fribourg, Switzerland
  1. Correspondence to Dr Philipp Suter; philipp.suter{at}


Takotsubo syndrome is an acute and often reversible condition, with initial presentation mimicking acute coronary syndrome. Typically, patients present with left ventricular regional wall motion abnormalities, without a corresponding coronary artery obstruction on angiography. Coexistence of a coronary artery disease is possible and may render the distinction between the two entities particularly challenging. We report the case of a 94-year-old woman with chest pain after an emotional upset and acute myocardial injury. Transthoracic echocardiogram (TTE) revealed a severely reduced left ventricular ejection fraction (LVEF) with apical ballooning. Coronary angiogram showed significant stenosis of the distal left main coronary artery and of the mid-left anterior descending artery, as well as a 30%–50% stenosis of the mid-distal right coronary artery. Revascularisation was deferred and antiplatelet as well as heart failure therapy begun. A repeat TTE 6 days later revealed a quasi-normalised LVEF. Ultimately, percutaneous coronary revascularisation of the left main and left anterior descending artery was performed, with favourable outcome at 6-month follow-up.

  • ischaemic heart disease
  • interventional cardiology

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  • HV and MS are joint first authors.

  • Contributors HV and MS wrote the initial draft. SC, YR, PS and DA reviewed the draft critically for important intellectual content. All authors were involved in the patient’s care, made substantial contributions to the conception of the work, approved the final version of the draft and agreed to be accountable for all aspects of the work.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.