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Peripartum considerations and challenges in the management of type IV Ehlers-Danlos syndrome
  1. Hazarathamma Makam1,
  2. Farah Siddiqui1,
  3. Asmita Patwardhan1 and
  4. Anil Darbar2
  1. 1Department of Obstetrics and Gynaecology, University Hospitals of Leicester NHS Trust, Leicester, UK
  2. 2Department of Anaesthesia and Intensive Care Medicine, Glenfield Hospital, University Hospitals of Leicester NHS Trust, Leicester, UK
  1. Correspondence to Dr Hazarathamma Makam; hazaramakam{at}gmail.com

Abstract

Ehlers-Danlos syndrome (EDS) is an uncommon heterogenous autosomal dominant multisystemic connective tissue disorder, which may potentially present with life-threatening emergencies. The prevalence of EDS of all subtypes is from 1 in 10 000 to 1 in 20 000. Pregnancy in women with type IV EDS poses significant challenges, necessitating the care of multidisciplinary team. Potential complications of type IV EDS include arterial dissection, arterial aneurysm, visceral rupture, excessive bleeding, tissue fragility and delayed wound healing. We present an interesting case of a pregnant woman with type IV EDS who had previous cerebrovascular complications and had a successful delivery in our tertiary centre following a collaborative approach to her care.

  • pregnancy
  • connective tissue disease
  • stroke
  • adult intensive care
  • haematology (incl blood transfusion)

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Footnotes

  • Contributors HM: involved in the clincal care of the patient, data collection, consenting the patient for writing the case report and writing the case up. FS, AP: Contribution in writing the reviewing the case report. AD: contribution in writting the anaesthetic implications in this particular case and clinical care of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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