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Giant coronary artery aneurysm as a feature of coronavirus-related inflammatory syndrome
  1. Kerrie Louise Richardson1,
  2. Ankita Jain1,
  3. Jennifer Evans2 and
  4. Orhan Uzun1
  1. 1Paediatric Cardiology, Noah's Ark Children's Hospital for Wales, Cardiff, UK
  2. 2General Paediatrics, Noah's Ark Children's Hospital for Wales, Cardiff, UK
  1. Correspondence to Dr Kerrie Louise Richardson; kerrie.richardson{at}


A 5-month-old female infant was admitted to hospital with a history of fever and rash during the recent coronavirus pandemic. She had significantly elevated inflammatory markers and the illness did not respond to first line broad spectrum antibiotics. The illness was later complicated by coronary artery aneurysms which were classified as giant despite treatment with intravenous immunoglobulin, steroids and immunomodulators. The infant had COVID-19 antibodies despite an initial negative COVID-19 PCR test. This case highlights the association of atypical Kawasaki like illness and paediatric multisystem inflammatory syndrome-temporarily associated with COVID-19 infection.

  • cardiovascular medicine
  • paediatrics
  • COVID-19

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  • Contributors KLR, OU, AJ and JE all contributed to the concept and writing of this case report. All authors critically appraised and edited the final version of the manuscript and have full responsibility of the data presented. All authors including the parents have seen and approved the final version of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.