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COVID-19-induced postural orthostatic tachycardia syndrome treated with ivabradine
  1. Jenna Stephanie O'Sullivan1,
  2. Andrew Lyne2 and
  3. Carl J Vaughan1
  1. 1Cardiology, Mercy University Hospital, Cork, Ireland
  2. 2Tower Medical Centre, Cork, Ireland
  1. Correspondence to Jenna Stephanie O'Sullivan; osullivanjennas{at}


A 22-year-old woman was referred with exertional dyspnoea and chest tightness 3 weeks following a diagnosis of COVID-19. Evaluation revealed a resting sinus tachycardia and criteria for postural orthostatic tachycardia syndrome were met. After non-pharmacological interventions failed to yield symptomatic improvement, ivabradine was commenced. This intervention was followed by a substantial improvement in the patient’s exercise tolerance and energy levels and an objective reduction in supine and standing heart rate.

  • COVID-19
  • cardiovascular system
  • cardiovascular medicine

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  • Contributors AL reviewed the patient in the first instance and identified the patient as having symptoms consistent with a post-COVID phenomenon. He referred the patient to CV who reviewed the patient with JSO, diagnosed postural orthostatic tachycardia syndrome and advised commencement of ivabradine. JSO collated the data and undertook literature review prior to writing up the case report. CV edited the case report. AL has conducted follow-up reviews of the patient.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.