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Graves’-induced prothrombotic state and the risk of early-onset myocardial infarction
  1. Meilyr Dixey,
  2. Alice Barnes and
  3. Fiqry Fadhlillah
  1. Imperial College Healthcare NHS Trust, London, UK
  1. Correspondence to Dr Fiqry Fadhlillah; fiqry.fadhlillah{at}


Hyperthyroidism represents a state of hypercoagulability and hypofibrinolysis, which predisposes an individual to the increased risk of thromboembolism. We present a case of a 25-year-old patient presenting with an acute myocardial infarction secondary to plaque rupture with thrombotic occlusion of proximal left anterior descending artery, in a patient known to have Graves’ disease. She had a sudden ventricular fibrillation arrest and a precordial thump given and cardiopulmonary resuscitation started. She successfully underwent cardiac catheterisation. Subsequent thyroid function tests showed she was in active thyrotoxicosis.

  • cardiovascular medicine
  • endocrine system
  • emergency medicine

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  • Contributors MD and AB were involved in information gathering and drafting the manuscript. FF wrote the discussion section of the manuscript. All authors reviewed and approved the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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