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Castleman’s disease masquerading as pancreatic neuroendocrine tumour
  1. Deepika Gunda1,
  2. Jack Naughton1,
  3. Sean Gregory Stevens2 and
  4. Marcos V Perini1,3
  1. 1Department of Surgery, Austin Health, Heidelberg, Victoria, Australia
  2. 2Department of Surgery, Austin Precinct, University of Melbourne, Melbourne, Victoria, Australia
  3. 3Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Melbourne, Victoria, Australia
  1. Correspondence to Dr Deepika Gunda; deepika.gunda{at}austin.org.au

Abstract

Castleman’s disease (CD) is a rare lymphoproliferative disorder. This case report, to the best of our knowledge, is the first report of CD simulating a pancreatic neuroendocrine tumour . The patient was a 58-year-old woman who initially presented with bilateral iritis and underwent investigation for possible systemic rheumatological disease. CT of the chest demonstrated an incidental finding of a well-demarcated retropancreatic mass. As the mass was found to enhance on DOTATATE (tetraazacyclododecanetetraacetic acid-DPhe1-Tyr3-octreotate) positron emission tomography, a diagnosis of pancreatic neuroendocrine tumour was made. The patient underwent an open distal pancreatectomy and splenectomy. Histopathological examination revealed the unexpected diagnosis of hyaline vascular CD of a lymph node posterior to the pancreas. After 2 years of follow-up, there is no evidence of disease recurrence.

  • pancreas and biliary tract
  • general surgery
  • gastrointestinal surgery

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Footnotes

  • Contributors The following contributions were made by the respective authors: DG was involved in data collection, writing, editing and the submission process. JN was involved in conception, data collection and writing. SS was involved in conception, writing, editing and the submission process. MP was involved in conception and editing.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer-reviewed.

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