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Spontaneous regression of oesophageal squamous cell carcinoma
  1. Haroon Khan1,
  2. Patrick Casey2,
  3. Stephen Hayes1,
  4. Ajay Tokala1 and
  5. Javed Sultan1
  1. 1Department of Oesophagogastric Surgery, Salford Royal Hospital, Salford, Manchester, Salford, UK
  2. 2General Surgery, Lancashire Teaching Hospitals NHS Foundation Trust, Preston, UK
  1. Correspondence to Patrick Casey; patrickcasey{at}live.co.uk

Abstract

Partial or complete spontaneous regression (SR) of cancer is unusual, particularly in patients with oesophageal cancer. This case report describes a patient with biopsy-proven squamous cell carcinoma of the oesophagus which spontaneously regressed without any treatment. Regression of the primary tumour was confirmed on histological examination of the resected specimen. The process of SR remains an enigma, but potential mechanisms are considered.

  • cancer intervention
  • COVID-19
  • oesophagus
  • pathology

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Footnotes

  • Twitter @patrickofcasey

  • Contributors HK and PC were involved in the conception, planning, critical analysis and writing of the manuscript. SH was involved in acquisition and interpretation of data, along with critical analysis and revision of the final manuscript. AT and JS were involved in the conception, planning, critical analysis and revision of the final manuscript. All authors made a substantial contribution to the manuscript and are accountable to the integrity of the article.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.