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A rare case of atypical bone marrow sarcoidosis without pulmonary involvement in a Japanese woman
  1. Maki Iwata1,2,
  2. Tatsuya Kodama1,2,
  3. Hiroaki Takeo3 and
  4. Norikazu Mataki1,2
  1. 1Internal Medicine, Mishuku Hospital, Megro, Japan
  2. 2Department of Internal Medicine, Self-Defence Forces Central Hospital, Setagaya, Japan
  3. 3Department of Pathology, Self-Defence Forces Central Hospital, Setagaya, Japan
  1. Correspondence to Maki Iwata; 1254maki{at}


Sarcoidosis is a systemic granulomatous disease of unknown origin characterised by the presence of non-caseating granulomatous lesions. Extrapulmonary sarcoidosis with bone marrow involvement is rare and even more so without pulmonary involvement. Here, we describe a case of 69-year-old woman diagnosed as having bone marrow and hepatic sarcoidosis without pulmonary involvement based on 18F-fluorodeoxyglucose positron emission tomography findings. She was successfully treated with systemic glucocorticoid therapy.

  • general practice / family medicine
  • medical management
  • immunology

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  • Contributors MI wrote the initial draft of the manuscript. TK, HT and NM assisted in the preparation of the manuscript. All authors approved the final version of the manuscript and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.