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Isolated cortical vein thrombosis in a young male adult
  1. Lourdu Sireesha Pentareddy,
  2. Corina Cristina Nava Suarez,
  3. Darell Caesario and
  4. Stephen Jesmajian
  1. Department of Medicine, Montefiore New Rochelle Hospital, New Rochelle, New York, USA
  1. Correspondence to Dr Lourdu Sireesha Pentareddy; sireesha.abraham{at}


Isolated cortical vein thrombosis (ICVT) is a rare entity and accounts for only 6.3% of cerebral venous and sinus thrombosis. ICVT is an uncommon cause of seizures in young adults. We present a 27-year-old man with no medical history who presented with dizziness, loss of consciousness and a seizure-like episode. The patient was found to have an elevated D-dimer and brain imaging revealed ICVT. The patient was started on anticoagulation and antiseizure medications. A high index of suspicion for uncommon aetiologies for new-onset seizure, especially in the young, is key to accurate diagnosis of ICVT. Evaluation and work-up should include detailed physical examination, along with appropriate brain imaging and testing for other conditions that predispose venous thrombosis. In the setting of the SARS-CoV-2 pandemic, testing for COVID-19 may also be warranted. Rapid diagnosis and full anticoagulation can help avoid debilitating complications and long-term sequelae.

  • epilepsy and seizures
  • neuroimaging
  • radiology

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  • Contributors LSP conceived the idea of creating a journal entry based on the uniqueness of the case. CCNS and DC both contributed by doing research to verify the uniqueness of the case. All authors worked together on putting together the final manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.