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Medically managed prosthetic valve endocarditis caused by Salmonella enteritidis
  1. Gavin Connolly1,
  2. Mita Kale2 and
  3. Andrew Ustianowski1
  1. 1Infectious Diseases, Northern Care Alliance NHS Group, Manchester, UK
  2. 2Cardiology, Northern Care Alliance NHS Group, Manchester, UK
  1. Correspondence to Dr Gavin Connolly; gavinconnolly{at}


Infective endocarditis is associated with morbidity and mortality even when appropriately treated. It can be more complicated to treat when prosthetic material is present, often necessitating surgical revision as well as antimicrobial therapy. Endocarditis caused by gram-negative bacilli is a rare occurrence, with some literature and expert opinion suggesting superior outcomes with combined surgery and antibiotics when a prosthetic valve is involved. In cases where the prosthetic valve is well-functioning and undamaged, or cardiothoracic surgery represents a significant operative risk, it can be unclear how best to proceed. This report documents a case of Salmonella enterica subspecies enterica serovar enteritidis endocarditis of a mechanical mitral valve. The patient was managed with 6 weeks of intravenous antibiotics followed by suppressive oral antibiotic therapy. They remain in good health at 24 months.

  • valvar diseases
  • infections
  • infectious diseases
  • cardiothoracic surgery

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  • Contributors GC performed the literature search, drafted and revised the paper. He is the guarantor. MK managed the case and revised the draft paper. AU had the idea for the paper, managed the case and revised the draft paper.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.