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Case report
COVID-19 in a premature infant
  1. David CE NG,
  2. Ling Chin,
  3. Pauline Poh Ling Choo and
  4. Umathevi Paramasivam
  1. Pediatrics, Hospital Tuanku Ja'afar Seremban, Seremban, Negeri Sembilan, Malaysia
  1. Correspondence to Dr David CE NG; davidngce{at}gmail.com

Abstract

We report a case of COVID-19 in a 29-week preterm infant. This child is the youngest reported case of SARS-CoV-2 infection in Malaysia, and to the best of our knowledge, one of the youngest documented cases of established vertical transmission of SARS-CoV-2 reported in literature. Our report highlights the clinical course, timelines of viral shedding by real-time reverse transcription-PCR and antibody seroconversion in a premature infant infected with SARS-CoV-2. In addition, we discuss the challenges faced in managing a preterm infant infected with SARS-CoV-2 and the knowledge gaps that need to be explored.

  • COVID-19
  • neonatal health
  • congenital disorders

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

http://dx.doi.org/10.1136/bcr-2021-243783

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    Footnotes

    • Contributors DCEN participated in the clinical care of the patient, conceptualised the manuscript, drafted the initial manuscript, reviewed and revised the manuscript. LC participated in the clinical care of the patient, coordinated data collection and drafted the initial manuscript. PPLC participated in the clinical care of the patient, supported literature review, revised the manuscript and added intellectual content. UP participated in the clinical care of the patient, supported literature review, revised the manuscript and added intellectual content. All authors approved the final manuscript as submitted and agree to be accountable for all aspects of the work.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.