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Bilateral simultaneous non-arteritic ischaemic optic neuropathy: a rare complication of idiopathic systemic capillary leak syndrome (SCLS)
  1. Yan Ning Neo,
  2. Manvi Sobti and
  3. Hadi Zambarakji
  1. Ophthalmology Department, Whipps Cross University Hospital, Barts Health NHS Trust, London, UK
  1. Correspondence to Dr Yan Ning Neo; aning88{at}


We report a case of bilateral symmetrical superior visual field defects in a 72-year-old man first reported during the recovery from systemic capillary leak syndrome (SCLS). During the acute illness, he required extensive and prolonged fluid replacement and mechanical ventilation for severe hypotension, shock and multiorgan dysfunction. His visual field defect and optic nerve changes were consistent with a diagnosis of ischaemic optic neuropathy. These remained unchanged over 3 years and he retained excellent 6/7.5 visual acuity bilaterally. We hypothesised the mechanism of bilateral segmental infarction of the optic nerve head to be caused by the hypercoagulable and hypovolaemic state, in addition to pre-existing vascular disease and hypertension. This case highlights the importance of including optic nerve examination in the management plan of SCLS, particularly in individuals with underlying vascular risk factors.

  • neuro-ophthalmology
  • ophthalmology
  • visual pathway
  • adult intensive care

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  • Contributors HZ, YNN and MS conceived the idea for the case report. YNN wrote the manuscript. All authors contributed to the editing of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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