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Case report
Delayed, transient and self-resolving neutropenia following COVID-19 pneumonia
  1. Victoria Marie Ferreira Mank1,
  2. Jeffrey Mank2,
  3. Jenie Ogle1 and
  4. Jefferson Roberts3
  1. 1Internal Medicine, Tripler Army Medical Center, Honolulu, Hawaii, USA
  2. 2University of New England, Biddeford, Maine, USA
  3. 3Rheumatology, Tripler Army Medical Center, Honolulu, Hawaii, USA
  1. Correspondence to Dr Victoria Marie Ferreira Mank; victoriammank{at}gmail.com

Abstract

A novel coronaravirus, identified as SARS-CoV-2, spread throughout the world in 2020. The COVID-19 pandemic has led to many discoveries and clinical manifestations. A young patient is presented with new, self-resolving neutropenia presenting weeks after a prolonged hospital stay for COVID-19 pneumonia. Workup included analysis for underlying infection, nutritional abnormalities, malignancy, medication and toxin exposure, all of which were negative. From 2020 to the present, few reports have described neutropenia associated with a recent COVID-19 infection. In particular, no reports have described a delayed presentation of neutropenia. The authors would like to propose that the significant inflammatory response associated with COVID-19 is likely what led to this patient’s postviral neutropenia. Furthermore, in young healthy patients, bone marrow biopsy may be deferred and a watchful-waiting approach may be taken to assess for neutropenia resolution.

  • COVID-19
  • haematology (incl blood transfusion)
  • medical management
  • haematology (drugs and medicines)
  • infectious diseases

This article is made freely available for use in accordance with BMJ’s website terms and conditions for the duration of the covid-19 pandemic or until otherwise determined by BMJ. You may use, download and print the article for any lawful, non-commercial purpose (including text and data mining) provided that all copyright notices and trade marks are retained.

https://bmj.com/coronavirus/usage

https://doi.org/10.1136/bcr-2021-242596

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    Footnotes

    • Contributors All authors participated in the writing of this manuscript. VMFM wrote the majority of the manuscript, edited, performed literature review and was active in caring for the patient. JO edited the manuscript, assisted with background research and cared for the patient. VM and JO obtained both verbal and virtual written consent from the patient. JM assisted with background research, writing the manuscript and editing. JR assisted with editing the final manuscript and background research.

    • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

    • Competing interests None declared.

    • Provenance and peer review Not commissioned; externally peer reviewed.