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Orbital metastasis from hepatocellular carcinoma revealed by sudden exophthalmos
  1. Maria Baldovin1,
  2. Athanasios Saratziotis2,
  3. Claudia Zanotti1 and
  4. Enzo Emanuelli1
  1. 1Department of Neuroscience, University of Padova, Padova, Veneto, Italy
  2. 2Otolaryngology-Head and Neck Surgery, General University Hospital of Larissa, Larissa, Greece
  1. Correspondence to Dr Athanasios Saratziotis; asaratziotis{at}gmail.com

Abstract

Orbital metastases represent a rare condition and only 33 cases of metastases from hepatocellular carcinoma (HCC), usually revealed by slowly progressive exophthalmos, have been described in the literature. A 62-year-old man affected by HCC reported a sudden left exophthalmos and amaurosis. A cranial CT scan revealed pathological tissue occupying the superior portion of the orbit. During endoscopic decompression of the optic nerve, an active venous intraorbital haemorrhage was noted. Following angiography, permanent occlusion was performed on a neoforming circulus fed by ramification of the anterior deep temporal artery, anterior ramification of the superficial temporal artery and sphenoidal ramification of the medial meningeal artery. A percutaneous incisional orbital biopsy showed features of metastatic foci of HCC. This is the first description of orbital metastasis from HCC revealed by a sudden exophthalmos.

  • otolaryngology / ENT
  • ophthalmology
  • head and neck surgery
  • surgical oncology

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Footnotes

  • Contributors MB contributed to planning to conception and design acquisition of data drafting the work and final approval of the version to be published. AS contributed to planning to conception and design acquisition of data drafting the work and final approval of the version to be published. CZ contributed to planning to conception and design acquisition of data drafting the work and final approval of the version to be published. EE contributed to planning to conception and design acquisition of data drafting the work and final approval of the version to be published.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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