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Bilateral chorea following severe traumatic brain injury treated with risperidone
  1. Daniel Krasna,
  2. Erica Montgomery,
  3. Jacob Koffer and
  4. Miriam Segal
  1. Physical Medicine and Rehabilitation, Moss Rehabilitation Hospital, Elkins Park, Pennsylvania, USA
  1. Correspondence to Dr Daniel Krasna; krasna.daniel{at}


A functionally independent man in his 20s with a history of intellectual disability and epilepsy and family history of Huntington’s disease suffered a severe traumatic brain injury. Postinjury, bilateral chorea rendered him dependent for all activities of daily living. Risperidone provided a significant reduction of chorea, decreasing the overall burden of care. Movement disorders are a common sequela of brain injury. Currently, there are no best treatment guidelines for chorea in patients with brain injury. To the authors’ knowledge there have been no case reports describing the effects of brain injury on patients with a primary movement disorder. Risperidone was an effective treatment in this case. Further research is needed to establish guidelines for treatment of movement disorders following brain injury and to better understand the effect of brain injuries on primary movement disorders.

  • neurology (drugs and medicines)
  • trauma
  • movement disorders (other than Parkinsons)
  • trauma CNS /PNS
  • rehabilitation medicine

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  • Contributors DK, EM and JK contributed to the research and writing of the case report with DK coordinating the efforts. MS served as the attending physician for all the trainees during the patient’s hospital stay, guided the care and interventions, and helped edit the case report for content and clarity.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.