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Perioperative considerations in the management of cold agglutinin disease in laparoscopic surgery
  1. Yisi D Ji1,
  2. Paul M Cavallaro2 and
  3. Britlyn D Orgill1,3
  1. 1Harvard Medical School, Boston, Massachusetts, USA
  2. 2Department of Surgery, Massachusetts General Hospital, Boston, Massachusetts, USA
  3. 3Department of Anesthesia, Critical Care and Pain Medicine, Massachusetts General Hospital, Boston, Massachusetts, USA
  1. Correspondence to Dr Yisi D Ji; yisi_ji{at}


An 80-year-old man with idiopathic cold agglutinin disease presented with acute cholecystitis. We describe operating room and anaesthetic considerations for patients with cold agglutinin disease and measures that can be taken to prevent disease exacerbation in this case report. Multidisciplinary collaboration and planning between the operative room staff, anaesthesia team and surgical team are needed to ensure safe surgery and optimal patient outcomes.

  • anaesthesia
  • general surgery
  • haematology (incl blood transfusion)

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  • Contributors YDJ, PMC and BDO contributed equally to the manuscript and idea conception.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.