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Retinal vasoproliferative tumour secondary to retinitis pigmentosa sine pigmento
  1. Albert John Bromeo1,
  2. Sweet Jorlene Lerit1,
  3. Amadeo Veloso1 and
  4. Gary John Mercado2,3
  1. 1Asian Eye Institute, Makati, Philippines
  2. 2Eye and Vision Institute, The Medical City, Pasig, Philippines
  3. 3Department of Ophthalmology and Visual Sciences, Philippine General Hospital, University of the Philippines Manila, Manila, Philippines
  1. Correspondence to Dr Albert John Bromeo; albert.bromeo{at}


Retinitis pigmentosa can be associated with exudative vasculopathy in rare instances, which can manifest as retinal vasoproliferative tumours. We present the case of a 33-year-old woman previously diagnosed with retinitis pigmentosa sine pigmentosa in both eyes. She was asymptomatic and just came in for a routine follow-up eye examination. Thorough examination of the peripheral retina on the right eye revealed a dome-shaped retinal tumour with a feeder vessel and surrounding exudative changes at the superotemporal periphery, consistent with a secondary retinal vasoproliferative tumour from retinitis pigmentosa. She subsequently underwent focal laser photocoagulation of the tumour which resulted in tumour stabilisation. While exudative vasculopathy is very uncommon in retinitis pigmentosa, ophthalmologists need to be aware of its occurrence in such patients. Vision loss may occur from exudation, haemorrhage, retinal detachment and neovascularisation. A thorough examination of the peripheral retina is warranted in these cases.

  • ophthalmology
  • retina
  • oncology
  • head and neck cancer

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  • Contributors SJL and AJB provided substantial contributions to the conception or design of the work as well as the acquisition, analysis or interpretation of data for the work. AV was the primary physician in charge of the case. GJM was consulted regarding the diagnosis and management of the case. All authors gave final approval of the version to be published and agree to be accountable for all aspects of the work in ensuring that questions related to the accuracy or integrity of any part of the work are appropriately investigated and resolved.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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