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Rhabdomyolysis and severe biphasic disturbance of calcium homeostasis secondary to COVID-19 infection

Abstract

We report a case of severe hypercalcaemia secondary to rhabdomyolysis in a woman with COVID-19 (SARS CoV-2) infection. The patient presented with myalgia and anuria with an acute kidney injury requiring haemodialysis. Creatine kinase peaked at 760 000 IU/L. A biphasic calcaemic response was observed with initial severe hypocalcaemia followed by severe, symptomatic hypercalcaemia, persistent despite haemodialysis. Control of the calcium levels was achieved by continuous haemofiltration.

  • endocrine system
  • renal system
  • calcium and bone
  • adult intensive care
  • acute renal failure

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