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Case report
Rare presentation of antisynthetase syndrome complicated by myocarditis resulting in sustained ventricular tachycardia


We report a complex case of a 66-year-old female patient with a diagnosis of interstitial lung disease (ILD) that was later correctly identified as an antisynthetase syndrome. This was only diagnosed after an episode of sustained ventricular tachycardia secondary to myocarditis. In this case report, we focus on the clinical features of this rare autoimmune condition and aim to provide useful tips to both general medical professionals and cardiologists to achieve correct differential diagnosis according to the updated international guidelines and recommendations. Early diagnosis is especially important due to the possible arrhythmogenic complications and the high mortality and morbidity associated with ILD and cardiac abnormalities.

  • cardiovascular medicine
  • arrhythmias
  • interstitial lung disease
  • rheumatology
  • connective tissue disease

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