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Kawasaki disease with acute myocarditis in an adolescent
  1. Masato Shimizu1,
  2. Toshio Kaneda2,
  3. Nagaaki Sekino3 and
  4. Takashi Nishizawa4
  1. 1Intensive Care Unit/Cardiology, Yokohama Minami Kyosai Hospital, Yokohama, Japan
  2. 2Cardiology, Yokohama Minami Kyosai Hospital, Yokohama, Japan
  3. 3Intensive Care Unit, Yokohama Minami Kyosai Hospital, Yokohama, Japan
  4. 4Pediatrics, Yokohama Minami Kyosai Hospital, Yokohama, Japan
  1. Correspondence to Dr Masato Shimizu; mst-smz{at}


A previously healthy 16-year-old adolescent was admitted to our hospital with fever, sore throat, diarrhoea, strawberry tongue, rashes on lower extremities, and pain in the neck, abdomen and joints. He was initially diagnosed with IgA vasculitis triggered by acute pharyngitis. Despite antibiotic treatment, he gradually developed multiorgan failure and cardiac shock. Cardiac catheterisation did not show any signs of coronary artery disease. Subsequently, he developed serious rhabdomyolysis and peripheral extremity necrosis, suggesting peripheral arteritis. Although blood culture results were negative, he received endotoxin adsorption therapy, but it was ineffective. Hence, we suspected Kawasaki disease (KD). We administered high-dose intravenous immunoglobulin therapy (2 g/kg), which was effective. He gradually recovered without major complications and was given ambulatory discharge 43 days after admission. Early diagnosis and administration of intensive care in adolescents with KD with acute myocarditis are critical but challenging.

  • cardiovascular medicine
  • heart failure
  • intensive care

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  • Contributors The contributions of all authors are as follows: MS, the first and corresponding author, treated the patient with TK, and drafted this manuscript. NS cooperated in the treatment as a director of intensive care medicine. TN gave clinical support and important advice for this case as a paediatric cardiologist, and revised the manuscript for important intellectual content, and gave final approval of the manuscript submitted.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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