Burkitt lymphoma (BL) is a rare, mature, fast-growing and highly aggressive B-cell neoplasm. It has a high-proliferation rate with distinctive genetic changes in the C-MYC oncogene. Treatment usually requires intense and frequent chemotherapy regimens with central nervous system prophylaxis as the usual regimens used for other non-Hodgkin’s lymphoma yield poor survival in BL. This report discusses a patient who was diagnosed with a stage II, high-grade BL who received one cycle of intense chemotherapy and refused further treatment. That patient remained in complete remission in his last follow-up; 7 years from diagnosis without requiring other therapies for his lymphoma.
- cancer intervention
- haematology (incl blood transfusion)
- head and neck cancer
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Contributors AAS: primary author: interviewed and got the patient’s consent, wrote the manuscript with a detailed literature review, provided most of the contribution to the revised manuscript. NM: helped in writing and finalising the manuscript especially with the initial proofreading. DS: haematology/oncology attending who was the main physician on the patient’s case, did the final and detailed revision of the manuscript on both revisions. SL: read the pathology slides and helped in choosing the best description of the slides’ in the manuscript based on the biopsy.
Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.
Competing interests None declared.
Provenance and peer review Not commissioned; externally peer reviewed.
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