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Gianotti-Crosti syndrome: a challenging exanthema
  1. Anaísa Afonso1,
  2. Joana Cachão1,
  3. Vitor Laerte Pinto Junior2 and
  4. Teresa Gouveia1
  1. 1Department of Pediatrics, Centro Hospitalar de Setúbal EPE, Setúbal, Portugal
  2. 2Department of Infectious Diseases, Centro Hospitalar de Setubal EPE, Setúbal, Portugal
  1. Correspondence to Dr Joana Cachão; joanacbc{at}hotmail.com

Abstract

Gianotti-Crosti syndrome (GCS) is a self-limited condition, mainly affecting children younger than 6 years, less common in adolescents and adults. It consists of a viral exanthema with papular lesions with a flat top and symmetrical distribution, affecting predominantly extremities, gluteal region and extensor surfaces. It is often associated with viral infections but can also be related to bacterial infections, vaccination or be idiopathic. In this report, we present a case of GCS in a 13-year-old healthy female adolescent who presented with fever, odynophagia, prostration and diffuse maculopapular rash. The diagnosis of infectious mononucleosis due to infection by the Epstein-Barr virus was established. On the second week of the disease, a clinical recrudescence occurred, with worsening of the fever and modification of the exanthema characteristics. GCS is often an underdiagnosed entity. The differential diagnosis of viral exanthema can prove to be challenging and clinical suspicion is essential to achieve the diagnosis.

  • paediatrics (drugs and medicines)
  • skin
  • infectious diseases

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Footnotes

  • Contributors AA: conception of the work, analysis and interpretation of data, drafting the work, final approval of the version published. JC: revising the work critically for important intellectual content, final approval of the version published. VLPJ: revising the work critically for important intellectual content, final approval of the version published. TG: revising it critically for important intellectual content, revising the work critically for important intellectual content, final approval of the version published.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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