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Multidrug-resistant novel Nocardia neocaledoniensis brain abscess in sarcoidosis
  1. Kasturi Hazarika1,
  2. Rasmi Ranjan Sahoo1,
  3. Digvijay Ekbote1,
  4. Ajai Kumar Dixit2,
  5. Rungmei S Marak2 and
  6. Anupam Wakhlu1
  1. 1Clinical Immunology and Rheumatology, King George's Medical University, Lucknow, Uttar Pradesh, India
  2. 2Department of Microbiology, Sanjay Gandhi Post Graduate Institute of Medical Sciences, Lucknow, Uttar Pradesh, India
  1. Correspondence to Dr Anupam Wakhlu; anupamwakhlu{at}


Central nervous system nocardiosis is a rare, life-threatening infection seen commonly in immunocompromised individuals. Nocardia neocaledoniensis is a novel species seldom causing infections in humans. We describe a patient of sarcoidosis on immunosuppression, who presented with altered sensorium due to a frontal lobe abscess secondary to N. neocaledoniensis infection. Despite appropriate and adequate antibiotic coverage, and timely surgical intervention, the patient succumbed to her illness on day 6 of hospitalisation. This case warrants the consideration of novel infections in patients on immunosuppression and the need for aggressive management.

  • infection (neurology)
  • infectious diseases
  • rheumatology

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  • Contributors KH and RRS: acquisition and interpretation of data, drafting and final approval of the manuscript. RSM and AW: interpretation of data, critical revision and final approval of the manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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