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Bilateral retinal artery occlusions as the first manifestation of extramedullary central nervous system involvement in relapsed acute myeloid leukaemia
  1. Diana Khair,
  2. Carl-Joe Mehanna,
  3. Alaa Bou Ghannam and
  4. Wajiha Jurdi Kheir
  1. Ophthalmology, American University of Beirut Medical Center, Beirut, Lebanon
  1. Correspondence to Dr Wajiha Jurdi Kheir; wk40{at}


Retinal artery and vein occlusion are rare devastating complications of central nervous system (CNS) leukaemic infiltrates of the retina and its vasculature. Only a handful of reports exist wherein CNS relapse presents with retinal vascular occlusions. This is usually accompanied by optic nerve swelling and subretinal infiltrates. We present a case of bilateral retinal artery occlusion as a first manifestation of CNS relapse in a patient with acute myeloid leukaemia without optic disc oedema and retinal infiltrates.

  • malignant disease and immunosuppression
  • breast cancer
  • chemotherapy
  • retina

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  • Contributors Study concept and design (DK, C-JM, WJK); Data collection (DK, C-JM); Analysis and interpretation of data (DK, ABG); Drafting of the manuscript (DK, C-JM, WJK); Critical revision of the manuscript (ABG, WJK); Supervision (ABG, WJK). All authors approve of the submission of this manuscript.

  • Funding The authors have not declared a specific grant for this research from any funding agency in the public, commercial or not-for-profit sectors.

  • Competing interests None declared.

  • Provenance and peer review Not commissioned; externally peer reviewed.

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